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Gene Loves Jezebel are a British rock band formed in the early 1980s by identical twin brothers Jay (born John) and Michael Aston. Gene Loves Jezebel's best-known songs include "Heartache", "Desire (Come and Get It)" (1986), "The Motion of Love" (1987), "Jealous" (1990) and "Break the Chain" (1993), as well as alternative club hits "Bruises" (1983), "Influenza (Relapse)" (1984) and "The Cow" (1985). "The Motion of Love" was the band's most successful UK single.

The name of the band is a reference to rock musician Gene Vincent and his song "Jezebel".

As the result of a rift between the Aston brothers in 1997 and ongoing legal issues, there are currently two incarnations of the band.