Thighpaulsandra is a Welsh experimental musician and multi-instrumentalist known mostly for performing on synthesizers and keyboards. He began his career working with Julian Cope in the late 1980s, becoming a member of Cope's touring band. A collaboration with Cope in 1993 followed, as the experimental duo Queen Elizabeth. In 1997, former Cope guitarist Mike Mooney invited Thighpaulsandra to fill in for the departing Kate Radley on a Spiritualized tour, where he remained until early 2008. In 1998 he also became a member of the experimental band Coil. He has subsequently released several solo albums.
He currently performs and records as part of URUK with Massimo Pupillo (of Italian band Zu) and UUUU, a band also featuring Valentina Magaletti and Graham Lewis and Matthew Simms both of Wire.