Lester B. Williams (June 24, 1920 – November 13, 1990) was an American Texas blues and electric blues guitarist, singer and songwriter. He is best known for his song "Winter Time Blues" and "I Can't Lose with the Stuff I Use". His main influence was T-Bone Walker.
Williams released several singles in the 1950s. His recording career lasted from 1949 to 1956, but he remained a stalwart of the Houston blues circuit for decades.