Matthew Skoller (born August 3, 1962) is an American Chicago blues harmonicist, singer, songwriter, and record producer. He has released five albums, as well as recording his harmonica playing on other musicians work, including John Primer, Lurrie Bell, Koko Taylor, H-Bomb Ferguson, Toronzo Cannon, Bernard Allison, Larry Garner, Big Daddy Kinsey, Big Time Sarah, Michael Coleman, and Harvey Mandel. On stage, he has supplied part of the backing to Big Time Sarah, Jimmy Rogers, and Deitra Farr.
The subject matter of his own song writing tackles issues of technology, information, inequality and upheaval. His band members have included guitarists such as Lurrie Bell and Larry Skoller, pianist and organist Sidney James Wingfield, bass player Willie "Vamp" Samuels, and the drummers Kenny "Beedy Eyes" Smith and Heitor Garcia.