Robert Wolfe Quine (December 30, 1942 – May 31, 2004) was an American guitarist. A native of Akron, Ohio, Quine worked with a wide range of musicians, though he himself remained relatively unknown. Critic Mark Deming wrote of "Quine's eclectic style embraced influences from jazz, rock, and blues players of all stripes, and his thoughtful technique and uncompromising approach led to rewarding collaborations with a number of visionary musicians."
His collaborators included Richard Hell & the Voidoids, Lou Reed (notably on The Blue Mask), Brian Eno, John Zorn, Ikue Mori, Marc Ribot, Marianne Faithfull (Strange Weather), Lloyd Cole, Matthew Sweet and Tom Waits.
Lester Bangs wrote that he was a "pivotal figure" and "the first guitarist to take the breakthroughs of early Lou Reed and James Williamson and work through them to a new, individual vocabulary, driven into odd places by obsessive attention to On the Corner-era Miles Davis." Quine was ranked 80th by Rolling Stone magazine's David Fricke in his list of "100 Greatest Guitarists".