0
Lisa Lopes
Lisa Lopes
American rapper and singer (1971–2002)
1
Tionne Watkins
Tionne Watkins
American singer-songwriter, the "T" in the girl-group TLC
2
Lil Mama
Lil Mama
American rapper from New York
3
Blaque
Blaque
band
4
Natina Reed
Natina Reed
American singer (1980-2012)
5
Drew Sidora
Drew Sidora
actress, singer
6
Destiny's Child
Destiny's Child
American rhythm and blues girl group
7
Dream
Dream
American pop girl group
8
The Pussycat Dolls
The Pussycat Dolls
American girl group and dance ensemble
9
New Edition
New Edition
American R&B group
10
NSYNC
NSYNC
American boy band
11
New Kids on the Block
New Kids on the Block
American boy band
12
Pink
Pink
American singer and songwriter
13
Spice Girls
Spice Girls
British girl group
14
Missy Elliott
Missy Elliott
American rapper, songwriter and record producer from Virginia
15
Mýa
Mýa
American R&B recording artist
16
New Boyz
New Boyz
American hip hop duo
17
Foxy Brown
Foxy Brown
American rapper, model, and actress
18
En Vogue
En Vogue
American vocal band from Oakland, California
19
Fifth Harmony
Fifth Harmony
American girl group
20
Babyface
Babyface
American singer, songwriter and record producer
21
Salt-N-Pepa
Salt-N-Pepa
American hip-hop group
22
Heart
Heart
American rock band
23
Beyoncé
Beyoncé
American artist
24
Matchbox Twenty
Matchbox Twenty
American band
25
SWV
SWV
American vocal group from New York City, New York
26
Aerosmith
Aerosmith
American rock band
27
Cyndi Lauper
Cyndi Lauper
American recording artist; singer, songwriter, actress and activist
28
Bon Jovi
Bon Jovi
rock band from the United States
29
Ciara
Ciara
American singer
30
Toni Basil
Toni Basil
American singer, actress, choreographer, dancer, and director
31
Usher
Usher
American singer, songwriter, dancer and actor
32
Justin Timberlake
Justin Timberlake
American singer, songwriter, record producer, and actor from Tennessee
33
Kimberly Cole
Kimberly Cole
American singer
34
Boys Like Girls
Boys Like Girls
band
35
3LW
3LW
American contemporary R&B group
36
Da Brat
Da Brat
musical artist
37
Wild Orchid
Wild Orchid
American pop group
38
Little Mix
Little Mix
British girl group
39
LMFAO
LMFAO
American electronic dance music duo
40
Dawn Robinson
Dawn Robinson
Anerican singer
41
Britney Spears
Britney Spears
American singer, songwriter, dancer, and actress
42
Lil' Kim
Lil' Kim
American rapper, actress and model from New York
Members, past and present

TLC is an American girl group whose original line-up consisted of Tionne "T-Boz" Watkins, and Lisa "Left Eye" Lopes. Formed in Atlanta, Georgia in 1990, the group enjoyed success during the 1990s. After the addition of Rozonda "Chilli" Thomas, they scored nine top-ten hits on the Billboard Hot 100, including four number-one singles "Creep", "Waterfalls", "No Scrubs", and "Unpretty". The group also recorded four multi-platinum albums, including CrazySexyCool (1994), which received a diamond certification from the Recording Industry Association of America (RIAA). TLC also became the first R&B group in history to receive the Million certification from the Recording Industry Association of Japan (RIAJ) for FanMail (1999).

Having sold over 65 million records worldwide, TLC is the best-selling American girl group. VH1 ranked TLC as the greatest female group, placing them at number 12 on the list of 100 Greatest Women in Music. Billboard magazine ranked TLC as one of the greatest musical trios, as well as the seventh-most successful act of the 1990s. The group's accolades include four career Grammy Awards, five MTV Video Music Awards, and five Soul Train Music Awards.

20 years after their debut, TLC was honored with Outstanding Contribution to Music at the 17th MOBO Awards and Legend Award at the 2013 MTV Video Music Awards Japan. Following Lopes' death in 2002, instead of replacing her, the remaining members chose to continue as a duo. In 2017, they released their eponymous fifth album TLC.